Author: Kathir J

  • TCG.Zone Announces Strategic Pivot to High-Value Collectible Assets

    New York, NY – 01/02/2026 – (SeaPRwire) – TCG.Zone (The Collectors Grid), a key player in the global collectibles infrastructure and ecosystem, has officially unveiled its strategic shift toward prioritizing investments in high-value, rare collectible assets. This strategic realignment underscores the company’s commitment to tapping into the long-term value and cultural significance of elite collectibles, with the recent participation in a high-profile international auction serving as a pivotal first step in this new direction.

    Recently, the world’s only Pokémon card graded PSA 10 – Pikachu Illustrator – once again became a focal point of global attention across the collectibles and cultural landscape. As a long-term contributor to TCG infrastructure and the broader collectibles ecosystem, The Collectors Grid(TCG.Zone) participated in and witnessed this historically significant moment.

    Recognized as one of the most iconic works in Pokémon card history, Pikachu Illustrator is distinguished not only by its extreme rarity, but also by its symbolic representation of Pokémon culture, artistic value, and generational memory.

    The Legendary Status of the World’s Only PSA 10

    According to publicly available information, the world’s only PSA 10 “Pikachu Illustrator” card is currently owned by Logan Paul. The card was involved in a high-profile transaction in 2022, valued at nearly USD 5.3 million, marking a defining milestone in the history of Pokémon card collecting.

    The Industry Significance of Goldin Auctions

    Although Logan Paul’s acquisition of the card did not take place through Goldin, the Goldin auction platform has continued to play an important role in the card’s contemporary circulation and visibility. As one of the world’s most influential high-end collectibles auction platforms, Goldin’s auction framework and the attention it generates brought renewed global focus to this legendary card, further positioning Pokémon cards within the broader mainstream collectibles market.

    Netflix Documentary Captures a Cultural Moment

    Amid the phenomenon-level attention generated by this card on the Goldin platform, Netflix documented the full auction process and produced a dedicated documentary. Approached from a cultural and historical perspective, the documentary highlights the unique position of Pikachu Illustrator within the modern collectibles ecosystem, elevating it beyond price alone and framing it as a lasting cultural reference.

    Global Participation and TCG.Zone’s Involvement

    The discussions and auction activity surrounding Pikachu Illustrator attracted participation from top collectors, institutions, and professional teams from around the world. TCG.Zone was among the active participants in the bidding process. During the auction, TCG.Zone submitted a bid of USD 5,000,000. Although the bid was ultimately surpassed by a higher offer, TCG.Zone remained deeply engaged throughout the process and witnessed this pivotal moment firsthand.

    Continuing to Follow the Card’s Future Trajectory

    In post-auction interviews, TCG.Zone stated that this participation does not mark an endpoint. The team will continue to closely monitor the movement and future trajectory of the world’s only PSA 10 Pikachu Illustrator, and does not rule out participating again should the right opportunity arise. This event represents more than an auction. It stands as a collective reflection on rarity, cultural identity, and long-term value.

    The story of Pikachu Illustrator continues to unfold,and remains an enduring chapter in the global history of Pokémon card collecting.

    About TCG

    The Collectors Grid is an on-chain infrastructure designed to formalize collectibles as a structured asset class. By integrating provenance, ownership, pricing, and settlement at the protocol level, it addresses long-standing inefficiencies in the global collectibles market. The platform enables institutional-grade transparency while preserving the unique characteristics of collectible assets. Positioned as a settlement layer rather than a marketplace, The Collectors Grid provides the foundational rails for liquidity, valuation, and long-term capital participation in cards, IP, and high-value collectibles.

    Social Links

    Twitter: https://x.com/tcgzoneofficial

    Instagram: https://www.instagram.com/tcgzoneofficial/

    Telegram: https://t.me/tcgzoneofficial

    Media Contact

    Brand : The Collectors Grid (tcg.zone)

    Contact: Annie

    Email: hi@tcg.zone

    Website: https://www.tcg.zone

  • Five Global Megatrends Highlighted at Open Dialogue Expert Forum at the Russia National Centre

    Moscow, Russia – 31/01/2026 – (SeaPRwire) – Expert Dialogues were held for the first time within the Open Dialogue framework at the Russia National Centre in Moscow on 30 January. The forum focused on five major megatrends shaping global economic, technological, and social development, bringing together international experts to explore how these forces will influence societies and industries in the decades ahead.

    Organized by the Russia National Centre in partnership with the Centre for Cross-Industry Expertise “The Third Rome” and supported by the Presidential Executive Office, the forum brought together experts from around the world to discuss economic, technological, and social transformations.

    Maksim Oreshkin, Deputy Head of the Russian Executive Administration for Global Trends, presented five key megatrends that, he said, are already shaping global development and will continue to influence the world in the coming decades.

    “By 2026, Open Dialogue has become an international platform uniting experts from across the world to discuss the future of the planet, the global economy, and society,” Oreshkin said. “Understanding these processes is essential for preparing for change and leveraging it in the interests of nations and, above all, people. Today, I will focus on five key megatrends — while not treating artificial intelligence as a separate trend, because it has already become an integral part of our lives.”

    1. A New Global Economic Paradigm: Globalisation 2.0

    A shift from traditional globalisation to a more decentralised system was described. BRICS+ countries now play a growing role in the global economy, technological development, and demographic trends, while the Global South is increasingly engaging in direct trade and national-currency settlements.

    “Globalisation hasn’t ended; it has changed,” Oreshkin said. “Sovereignty — at state, social, and economic levels — is now the key to competitiveness. Only countries that preserve all three levels can lead in a multipolar world.”

    China, the USA, India, and Russia are identified as major global powers, while highlighting emerging growth centres such as Indonesia and “connector countries” like the United Arab Emirates. Digital platforms and decentralised networks are also becoming independent participants in the world economy.

    2. Platformisation and Institutional Automation

    The second megatrend highlights the rise of platforms and automation across all sectors. Platforms and algorithms are increasingly shaping decision-making in healthcare, education, finance, trade, and beyond.

    “Platform solutions enhance efficiency and reduce transaction costs through self-adjusting algorithms,” Oreshkin said. “Countries without technological sovereignty risk becoming dependent on external platforms, which can have strategic consequences during conflicts.”

    3. Transformation of the Global Financial System

    It was noted that traditional financial models face mounting challenges, including rising public debt, widening inequality, and geopolitical fragmentation. Technologies such as blockchain, artificial intelligence, and digital platforms are creating alternative financial mechanisms, including decentralised finance.

    “The traditional model of cross-border payments is under pressure. Decentralised systems and digital technologies are reshaping the financial system,” he said.

    4. Demographic Shifts and Challenges

    The fourth megatrend concerns global population dynamics. Global fertility rates have fallen sharply, with some countries facing critical declines. By the end of the 21st century, the working-age population may shrink significantly, while the proportion of elderly people rises, placing pressure on pension systems and social services.

    “Even in Africa, the ratio of elderly to working-age population will rise to 30%, and globally to 56%,” Oreshkin explained. “Education demand will decrease, but healthcare and social service needs will grow. These interconnected trends will amplify each other.”

    5. Human Capital Development in the Technological Era

    The final megatrend focuses on human capital in a rapidly changing technological environment.

    Autonomous systems, digital platforms, and artificial intelligence are transforming education, work, and healthcare, while biotechnologies expand human capabilities.

    “AI is both a challenge and an opportunity,” Oreshkin said. “It allows personalized learning paths and supports teachers.

    Professions are changing: mid-level specialists will be in demand, and companies must retrain employees from junior positions. The social sphere will also evolve, ensuring active longevity in the new demographic era.”

    Global Perspective

    Throughout the presentation, Oreshkin illustrated each trend with real-life examples from different continents: a manager from Asia, a farmer from Africa, and a homemaker from Eastern Europe. He highlighted that innovations in Africa could improve education and healthcare, Eastern Europe may see rising living standards and more efficient social systems, and Asia will require reskilling to meet changing labor demands.

    “The world has entered a period of significant change in finance, demography, and other spheres. States, companies, and individuals must be prepared. Those who understand and adapt will shape the future,” Oreshkin concluded.

    Open Dialogue on Air

    This year, Open Dialogue introduced a podcast format — Open Dialogue on Air — featuring global experts discussing key trends in international development. Participants include award-winning Chinese sci-fi writer Chen Qiufan, Dr. Selina Neri of the Future Readiness Academy, Dr. Rais Hussin of EMIR Research (Malaysia), Prof. Wang Feng of UC Irvine, and global strategist Dr. Parag Khanna.

    First held in April 2025 at the Russia National Centre, the Open Dialogue brought together over 3,000 experts from dozens of countries. By presidential decree, it will now be held annually.

    Social Links

    Telegram: https://t.me/gowithrussia

    VK: https://vk.com/gowithrussia

    OK: https://ok.ru/gowithrussia

    DZen: https://dzen.ru/gowithrussia

    Contact for the media

    Brand: Russia National Centre

    Contact: Media team

    Email: Pressa@russia.ru

    Website: https://russia.ru

    Essay Submission: https://dialog.russia.ru/en/

  • Paradex Confirms $DIME TGE Timeline and Expands Airdrop Allocation Following XP Season 2 Conclusion

    New York, NY – Paradex today announced the official conclusion of XP Season 2, marking a major milestone in the platform’s roadmap toward the upcoming $DIME Token Generation Event (TGE).

    As part of its continued commitment to trader-first incentive alignment, Paradex confirmed that 25% of $DIME’s fully diluted supply will be airdropped to all XP holders at TGE, with tokens fully unlocked at launch.

    In a significant expansion of community rewards, Paradex also revealed that Season 2 XP holders will receive 20% of the total token supply, up from the previously planned 15%, reinforcing the platform’s long-term focus on rewarding active ecosystem participation.

    The $DIME TGE is currently scheduled for late February or early March, following the Chinese New Year holiday, with the official date to be announced by the Paradex Foundation.

    XP Season 2: Major Growth and Final Week Distribution

    XP Season 2 represented a period of substantial growth for Paradex across every major protocol metric:

    • Average daily trading volume increased from $68M to $2.1B (31x)
    • Open Interest grew from $28M to $679M (24x)
    • Total Value Locked rose from $25M to $218M (9x)
    • Total users expanded from 4.1k to 70.3k (17x)

    During the final week of the season (January 23 to January 29), Paradex distributed 6 million XP directly to active user wallets, with additional rewards allocated through referral codes and affiliate programs.

    Users surpassing 25,000 XP during the final week also received exclusive BadgerBox drops.

    A final waitlist snapshot is scheduled for January 31 at 00:00 UTC.

    $DIME Airdrop Allocation Breakdown

    Paradex confirmed the following $DIME distribution structure at TGE:

    • 25% of total supply allocated to all XP holders (fully unlocked)
    • 20% dedicated specifically to Season 2 XP participants (increased from 15%)
    • 5% reserved for Pre-Season and Season 1 XP holders (unchanged)

    With half of the token supply dedicated to user rewards and participation, Paradex continues to position itself as a platform built around long-term ecosystem alignment.

    Token Generation Event Details

    • Token: $DIME
    • Timing: After Chinese New Year
    • Target Window: Last week of February or first week of March
    • Initial Listing: Paradex Spot Markets
    • Issuer: Paradex Foundation (official date forthcoming)

    XP Season 3 Launches February 1

    Looking ahead, Paradex announced that XP Season 3 will begin on February 1, shifting focus toward the next phase of ecosystem expansion, including:

    • Spot trading
    • Real-World Asset (RWA) Perpetuals
    • Options markets

    XP accumulation will begin immediately on February 1, while the first weekly XP distribution will occur post-TGE, allowing the team to prioritize a smooth and focused token launch.

    Paradex reiterated that the platform remains committed to transparent execution, continued incentive alignment, and rewarding the traders and builders who drive long-term ecosystem growth.

    About Paradex

    Paradex is a privacy-first, zero-fee on-chain perpetuals exchange focused on high-performance decentralized trading infrastructure for a global community of crypto participants.

    Website: https://paradex.trade/

    X (Twitter): https://x.com/paradex

    Discord: https://discord.gg/paradex

  • Paradex Confirms $DIME TGE Timeline and Expands Airdrop Allocation Following XP Season 2 Conclusion

    New York, NY – Paradex today announced the official conclusion of XP Season 2, marking a major milestone in the platform’s roadmap toward the upcoming $DIME Token Generation Event (TGE).

    As part of its continued commitment to trader-first incentive alignment, Paradex confirmed that 25% of $DIME’s fully diluted supply will be airdropped to all XP holders at TGE, with tokens fully unlocked at launch.

    In a significant expansion of community rewards, Paradex also revealed that Season 2 XP holders will receive 20% of the total token supply, up from the previously planned 15%, reinforcing the platform’s long-term focus on rewarding active ecosystem participation.

    The $DIME TGE is currently scheduled for late February or early March, following the Chinese New Year holiday, with the official date to be announced by the Paradex Foundation.

    XP Season 2: Major Growth and Final Week Distribution

    XP Season 2 represented a period of substantial growth for Paradex across every major protocol metric:

    • Average daily trading volume increased from $68M to $2.1B (31x)
    • Open Interest grew from $28M to $679M (24x)
    • Total Value Locked rose from $25M to $218M (9x)
    • Total users expanded from 4.1k to 70.3k (17x)

    During the final week of the season (January 23 to January 29), Paradex distributed 6 million XP directly to active user wallets, with additional rewards allocated through referral codes and affiliate programs.

    Users surpassing 25,000 XP during the final week also received exclusive BadgerBox drops.

    A final waitlist snapshot is scheduled for January 31 at 00:00 UTC.

    $DIME Airdrop Allocation Breakdown

    Paradex confirmed the following $DIME distribution structure at TGE:

    • 25% of total supply allocated to all XP holders (fully unlocked)
    • 20% dedicated specifically to Season 2 XP participants (increased from 15%)
    • 5% reserved for Pre-Season and Season 1 XP holders (unchanged)

    With half of the token supply dedicated to user rewards and participation, Paradex continues to position itself as a platform built around long-term ecosystem alignment.

    Token Generation Event Details

    • Token: $DIME
    • Timing: After Chinese New Year
    • Target Window: Last week of February or first week of March
    • Initial Listing: Paradex Spot Markets
    • Issuer: Paradex Foundation (official date forthcoming)

    XP Season 3 Launches February 1

    Looking ahead, Paradex announced that XP Season 3 will begin on February 1, shifting focus toward the next phase of ecosystem expansion, including:

    • Spot trading
    • Real-World Asset (RWA) Perpetuals
    • Options markets

    XP accumulation will begin immediately on February 1, while the first weekly XP distribution will occur post-TGE, allowing the team to prioritize a smooth and focused token launch.

    Paradex reiterated that the platform remains committed to transparent execution, continued incentive alignment, and rewarding the traders and builders who drive long-term ecosystem growth.

    About Paradex

    Paradex is a privacy-first, zero-fee on-chain perpetuals exchange focused on high-performance decentralized trading infrastructure for a global community of crypto participants.

    Website: https://paradex.trade/

    X (Twitter): https://x.com/paradex

    Discord: https://discord.gg/paradex

  • Cloudbet Academy Launches World Cup 2026 Betting Guide: Crypto Strategies and Tournament Insights

    Willemstad, Curaçao – Cloudbet, a leading crypto sportsbook and casino, today announces the release of the World Cup 2026 Betting Guide, a new free course in its Cloudbet Academy platform. Designed specifically for crypto users, this 35-minute open-access guide delivers targeted strategies and practical insights to help bettors navigate the expanded 48-team FIFA World Cup 2026, scheduled for June 11 to July 19, 2026.

    The FIFA World Cup consistently ranks as one of the most heavily bet-on sporting events globally, attracting billions in wagers each edition due to its massive scale, international reach, and cultural impact. Industry estimates for recent tournaments place global betting turnover in the tens of billions of dollars, with projections for 2026 suggesting even higher volumes given the tournament’s unprecedented 48-team format and 104 matches.

    A Cloudbet spokesperson says, “The 2026 World Cup is a prime moment for crypto bettors. On Cloudbet, with instant deposits and payouts in over 40 cryptocurrencies, you’re in the game within minutes. Stablecoins like USDT let you ride out volatility through the tournament, and low gas fees mean you can move fast when the odds shift. Want to back your country? Your club hero? You can, and with no red tape.”

    Hundreds of outrights, player props, team specials, group winners, and other futures markets are already live on Cloudbet. These cover everything from tournament winner and top goalscorer to assists leader and match-specific propositions, giving users immediate access to a broad spectrum of options. For high-stakes bettors, Cloudbet’s Whale Mode—launched just in time for the Super Bowl—enables VIP traders to automate large positions with precision, making it ideal for high-profile tournaments like the World Cup.

    The Academy, launched in late 2025, features three core tracks—Crypto Betting Basics, Sports Betting Fundamentals, and Betting Strategies & Analytics—that include interactive quizzes and rewards upon completion. The World Cup 2026 Betting Guide stands apart as the first tournament-specific course. It provides a focused, standalone deep dive that equips crypto users with crypto-optimized approaches to futures positioning, match betting, in-play tactics, and more.

    World Cup 2026 Betting Guide: 7 Key Modules

    The guide is structured across seven concise modules:

    1. World Cup 2026 basics and tournament format
       
       Breaks down the expanded 48-team format and how it creates inefficiencies across early group pricing, qualification paths, and futures markets.

       
    2. World Cup outright & futures betting
       
      Covers early positioning tactics, how to track odds shifts during qualification and the tournament, and how to use stablecoins to manage long-term volatility.

       
    3. How to place World Cup match bets
       
      Introduces group-stage vs knockout-stage dynamics and teaches contextual analysis beyond surface-level rankings.

       
    4. World Cup props, specials & group-based markets
       
      Focuses on Golden Boot, assist leaders, group winners, and other specials—plus how to adjust for neutral-venue effects.

       
    5. World Cup vs club football: What’s the difference?
       
      Explains key differences in tempo, tactics, pressure, and bankroll management between international and club football.

       
    6. World Cup live betting strategies
       
      Explores how to spot momentum swings in real time and use on-chain sentiment indicators to find edge in fast-moving markets.

       
    7. Advanced World Cup betting strategies & common mistakes (Advanced)
       
      Covers sharp techniques like futures hedging, accumulator timing, and how to avoid common pitfalls like public sentiment chasing and overconfidence.

    World Cup 2026 Qualification Snapshot

    As of January 2026, 42 nations have qualified, including co-hosts USA, Canada, and Mexico, plus major teams from every confederation such as Spain, England, France, Argentina, Brazil, Japan, and Morocco. The December 2025 draw has set the groups, and six final spots will be decided in March 2026 through UEFA play-offs and the inter-confederation tournament in Mexico.

    The Academy’s ‘World Cup Outright & Futures Betting‘ module covers more on this, including strategies for betting on group qualification, interpreting odds movements during play-offs, and positioning early in long-term markets amid uncertainty.

    A Cloudbet spokesperson noted, “With groups locked in and just a few spots left, now’s the window where early odds still reflect uncertainty. This is when sharp bettors get in—before pricing tightens after March and public money floods the markets in June.”

    Current World Cup 2026 Outright Odds on Cloudbet (as of January 2026)

    ●     Spain: 5.55 odds

    ●     England: 6.64 odds

    ●     France: 8.99 odds

    ●     Brazil: 9.11 odds

    ●     Argentina: 9.13 odds

    For the latest odds, visit Cloudbet.com.

    Access the World Cup 2026 Betting Guide now at cloudbet.com/en/academy/world-cup-2026-betting-guide

    About Cloudbet

    Founded in 2013, Cloudbet is the world’s longest-running crypto sportsbook and casino. Players can bet with over 40 cryptocurrencies across thousands of sports markets and a full portfolio of casino games, including slots, live dealers, and provably fair crypto titles.

    Cloudbet has processed millions of bets securely, offering sharp odds, high limits, instant crypto payouts, and 24/7 customer support.

    In 2024, Cloudbet introduced a welcome offer and loyalty program built for serious players—real cash rewards, daily cash drops, and 10% rakeback with no wagering requirements.

    From Premier League and NFL props to esports, tennis, and basketball, Cloudbet delivers the sharp action crypto bettors expect.

    Find us at Cloudbet.com, on Instagram @cloudbetofficial, and Twitter/X @Cloudbet.

     

    Media Contact

    Irene@media.cloudbet.com  

     

  • CMS (867.HK/8A8.SG): Ruxolitinib Phosphate Cream Obtained China NDA Approval, Becoming The First and Only Targeted Drug for Vitiligo in China

    SHENZHEN, CHINAChina Medical System Holdings Limited (“CMS” or the “Group”) is pleased to announce that its subsidiary, Dermavon Holdings Limited (“Dermavon”, an innovative pharmaceutical company specialized in skin health which is applying for a separate listing on the Main Board of The Stock Exchange of Hong Kong Limited, please refer to the announcement published by the Group on 22 April 2025 for details) received approval from the National Medical Products Administration of China (NMPA) on 30 January 2026 for the New Drug Application (NDA) of ruxolitinib phosphate cream (the “Product”) for the treatment of non-segmental vitiligo with facial involvement in children aged 12 years and older and adult patients. It is the first and only targeted drug approved in China for vitiligo, addressing a significant unmet clinical need.

    Ruxolitinib phosphate cream is the first and only drug approved by the U.S. Food and Drug Administration (FDA) and the European Medicines Agency (EMA) for repigmentation in nonsegmental vitiligo[1,2]. Prior to receiving formal NDA approval, the Group benefited from the “Early and Pilot Implementation” policy granted to the Hainan Free Trade Port and Lecheng Pilot Zone (“Lecheng Pilot Zone”), the “Hong Kong and Macau Medicine and Equipment Connect” policy, and the clinically urgently needed imported drug policies of the Beijing and Tianjin Free Trade Zones, and had already initiated the pilot application of ruxolitinib phosphate cream. Currently, Boao Super Hospital has prescribed ruxolitinib phosphate cream to over 7,000 patients with non-segmental vitiligo, and more than twenty hospitals in Guangzhou, Shenzhen, Dongguan, Foshan, Zhongshan, Zhuhai, Jiangmen, Huizhou, Beijing and Tianjin have provided prescription services for the Product, demonstrating its clinical potential.

    The product has shown positive results in both overseas clinical studies and the real-world study in China: in two identical Phase III double-blind, randomized, placebo-controlled studies (TRuE-V1 and TRuE-V2) conducted overseas, the proportion of patients achieving the primary efficacy endpoint of at least 75% improvement in the Facial Vitiligo Area Score Index (F-VASI 75) after 24 weeks of treatment with ruxolitinib phosphate cream was 29.9% in both studies, significantly higher than the 7.5% and 12.9% in the placebo groups, respectively. Continued use up to 52 weeks showed sustained repigmentation[3]. In accordance with the relevant regulations of the Lecheng Pilot Zone’s real-world data application pilot project, ruxolitinib phosphate cream underwent real-world study in China, demonstrating positive efficacy consistent with the results of overseas pivotal clinical studies. All secondary efficacy endpoints in both domestic and overseas clinical studies showed a benefit trend consistent with the primary efficacy endpoint, and the treatment effect for vitiligo continued to improve with prolonged treatment. Furthermore, according to safety monitoring data from the Lecheng Pilot Zone, no new safety event was identified, no adverse event (AE) leading to discontinuation or withdrawal of treatment occurred, and no study drug-related serious adverse event (SAE) occurred.

    This approval in vitiligo brings new hope for treatment to over 10 million vitiligo patients in China, addressing urgent clinical needs. At the same time, it will add to Dermavon’s product portfolio in the field of skin treatment, potentially synergizing with Dermavon’s commercialized innovative drug ILUMETRI (tildrakizumab injection), commercialized exclusive drug Hirudoid (mucopolysaccharide polysulfate cream), and a series of innovative drugs under development and dermatological skin care products, in terms of expert network and market resources, thereby potentially enhancing Dermavon’s position in the field of skin health.

    Furthermore, the Phase III clinical trial in China of ruxolitinib phosphate cream for the treatment of mild to moderate atopic dermatitis (AD) has achieved positive results. Currently, the Group is actively advancing the NDA for ruxolitinib phosphate cream for the treatment of AD in China, which, if approved, will provide a new treatment option for a broader patient population with AD in China.

    About Vitiligo

    Vitiligo is a chronic autoimmune disease characterized by depigmentation of the skin, which results from the loss of pigment-producing cells known as melanocytes. It is estimated that there are approximately 10.3 million vitiligo patients in China and non-segmental vitiligo patients account for approximately 8.2 million[4]. Existing therapies, such as topical corticosteroids (TCS) and topical calcineurin inhibitors (TCIs), have clinical limitations, with adverse reactions or limited efficacy with long-term use. The NDA approval of ruxolitinib phosphate cream successfully fills the gap in targeted drug treatment for vitiligo and is of great landmark significance. 

    More About Ruxolitinib Phosphate Cream

    Ruxolitinib phosphate cream (Opzelura®), a novel cream formulation of the selective JAK1/JAK2 inhibitor ruxolitinib developed by Incyte, is approved for the topical treatment of nonsegmental vitiligo in adult and patients aged 12 years and older, and for the short-term and non-continuous chronic treatment of mild to moderate AD in patients aged 2 years and older without immunodeficiency in the U.S. In Europe, ruxolitinib phosphate cream is approved for the treatment of non-segmental vitiligo with facial involvement in adults and adolescents from 12 years of age.

    The Group, through a subsidiary of Dermavon entered into a Collaboration and License Agreement with Incyte for ruxolitinib phosphate cream on 2 December 2022, obtaining an exclusive license to develop, register and commercialize the Product in Mainland China, Hong Kong Special Administrative Region, Macau Special Administrative Region, Taiwan Region and eleven Southeast Asian countries (the “Territory”) and a non-exclusive license to manufacture the Product in the Territory. The subsidiary of Dermavon has sublicensed the relevant rights for the Product outside Mainland China to the Group (excluding Dermavon and its subsidiary).

    Incyte has worldwide rights for the development and commercialization of ruxolitinib phosphate cream, marketed in the United States and Europe as Opzelura®. Opzelura® and the Opzelura® logo are registered trademarks of Incyte.

     

    About CMS

     

    CMS is a platform company linking pharmaceutical innovation and commercialization with strong product lifecycle management capability, dedicated to providing competitive products and services to meet unmet medical needs.

     

    CMS focuses on the global first-in-class (FIC) and best-in-class (BIC) innovative products, and efficiently promotes the clinical research, development and commercialization of innovative products, enabling the continuous transformation of scientific research into clinical practices to benefit patients.

     

    CMS deeply engages in several specialty therapeutic fields, and has developed proven commercialization capabilities, extensive networks and expert resources, resulting in leading academic and market positions for its major marketed products. CMS continues to promote the in-depth development in its advantageous specialty fields, strengthening the competitiveness of the cardio-cerebrovascular/ gastroenterology/ ophthalmology/ skin health businesses, bringing economies of scale in specialty fields. Among them, the skin health business (Dermavon) has become a leading enterprise in its field, and is proposed to be listed independently on the SEHK. Meanwhile, CMS continuously promotes the operation and development of its integrated R&D, manufacturing and commercialization chain in Southeast Asia and the Middle East, capturing growth opportunities in emerging markets to support the high-quality and sustainable development  of the Group.

     

    Reference:

    1. The U.S. FDA approval information can be found on the Incyte official website, as follows:

    https://investor.incyte.com/news-releases/news-release-details/incyte-announces-us-fda-approval-opzeluratm-ruxolitinib-cream

    1. The EMA approval information can be found on the Incyte official website, as follows:

    https://investor.incyte.com/news-releases/news-release-details/incyte-announces-european-commission-approval-opzelurar

    1. The clinical studies information can be found on the Opzelura® official website, as follows:

    https://www.opzelura.com/opzelura-prescribing-information

    1. China Insights Consultancy’s industrial report

     

    CMS Disclaimer and Forward-Looking Statements

    This press release is not intended to promote any products to you and is not for advertising purposes. This press release does not recommend any drugs, medical devices and/or indications. If you want to know more about the diagnosis and treatment of specific diseases, please follow the opinions or guidance of your doctor or other medical and health professionals. Any treatment-related decisions made by healthcare professionals should be based on the patients specific circumstances and in accordance with the drug package insert.

    This press release which has been prepared by CMS does not constitute any offer or invitation to purchase or subscribe for any securities, and shall not form the basis for or be relied on in connection with any contract or binding commitment whatsoever. This press release has been prepared by CMS based on information and data which it considers reliable, but CMS makes no representation or warranty, express or implied, whatsoever, and no reliance shall be placed on, the truth, accuracy, completeness, fairness and reasonableness of the contents of this press release. Certain matters discussed in this press release may contain statements regarding the Groups market opportunity and business prospects that are individually and collectively forward-looking statements. Such forward-looking statements are not guarantees of future performance and are subject to known and unknown risks, uncertainties and assumptions that are difficult to predict. Any forward-looking statements and projections made by third parties included in this press release are not adopted by the Group and the Company is not responsible for such third-party statements and projections.

     

    Media Contact

    Brand: China Medical System Holdings Ltd.

    Contact: CMS Investor Relations

    Email: ir@cms.net.cn

    Website: https://web.cms.net.cn/en/home/

     

  • From Martinsville to Watkins Glen: COOFANDY Continues Its NASCAR Journey with Joe Gibbs Racing in 2026 and Builds a New Chapter of Track Fashion in the New Season

    The renowned fashion apparel brand COOFANDY officially announced today that it will continue to serve as the primary sponsor for Joe Gibbs Racing‘s No. 20 team and driver Christopher Bell in 2026. The partnership will resume at Watkins Glen International on May 10, 2026, marking a further deepening and expansion of COOFANDY’s brand influence in NASCAR.

    COOFANDY made its debut at the NASCAR Cup Series Xfinity 500 race held at Martinsville Speedway last October. Through innovative initiatives such as track-side brand booths, custom-liveried show cars, and the “COOFANDY Victory Angels” cheer squad, the brand successfully integrated fashion into the racing scene, receiving positive feedback from fans and the industry.

    “Our initial partnership with the JGR No. 20 team and Christopher Bell in 2025 allowed us to witness the exciting collision of racing culture and brand philosophy, and we received an enthusiastic response from fans. We are thrilled to continue moving forward alongside JGR and Christopher Bell,” said Sidney Sun, Global Chief Marketing Officer of COOFANDY. “The NASCAR arena symbolizes passion and perseverance—each race is a journey filled with challenges and breakthroughs, which highly resonates with COOFANDY’s brand spirit of ‘Dress the Journey.’ We are committed to providing people with apparel that combines quality and style for every stage of life’s journey.”

    Driver Christopher Bell delivered a steady performance in the 2025 season, earning four trips to victory lane and a series leading 22 top ten finishes.

    “COOFANDY has been an outstanding partner since joining us,” said JGR Chief Communications Eric Schaffer. “They have used a creative approach through their support of our 20 team to enhance the fan experience. We are delighted to have COOFANDY back this season and looking forward to creating more memorable moments at the track.”

    This collaboration also signifies a further expansion of COOFANDY’s presence in sports marketing. The brand will continue to leverage NASCAR, an iconic national racing series, to communicate its philosophy of integrating fashion, sports, and lifestyle.

    As the 2026 NASCAR season is about to begin, the renewed partnership between COOFANDY and the JGR No. 20 team will become a signature spectacle of “Speed and Fashion” on the track. From custom-liveried race cars and immersive fan interactions to the profound interpretation of the “Dress the Journey” spirit, it promises to be an experience eagerly anticipated by racing enthusiasts and fashion audiences worldwide.

    For more information, please visit the COOFANDY website and Amazon storefront, or connect with COOFANDY on Facebook and Instagram.

    COOFANDY

    Charlotte Liu

    pr@coofandy.com

    New York, US

    https://coofandy.com

  • LEGENDARY HUMANITY, Listed on Gate.io, Launches RWA Market for Contemporary Artist Mago Nagasaka

    In Collaboration with MAGO Moon Museum, Opening the “$VIVI RWA MARKET”

     

    Singapore – LEGENDARY HUMANITY, a Singapore-based company listed on Gate.io, has announced the launch of the “$VIVI RWA MARKET,” a new Real World Asset (RWA) marketplace enabling the purchase of exhibited works by contemporary artist Mago Nagasaka. Developed in collaboration with the MAGO Moon Museum, this launch marks a significant milestone in LEGENDARY HUMANITY’s ongoing efforts to bridge cultural value and digital infrastructure through real-world assetization.

    Digitalizing Humanity’s Masterpieces Through AI 3D Scanning Technology – A New Purchasing Experience Led by LEGENDARY HUMANITY

    LEGENDARY HUMANITY PTE. LTD. (Headquarters: Singapore; CEO: Takamasa Suzuki) has officially opened the “$VIVI RWA MARKET,” an RWA marketplace where visitors can directly purchase artworks exhibited in the online museum “MAGO Moon Museum,” created by contemporary artist Shingo Nagasaka.

    This initiative forms part of the “VIVI PROJECT,” which aims to digitize humanity’s masterpieces into digital assets through high-precision, non-contact AI-integrated 3D scanning technology.

    Through this platform, visitors are able to acquire artworks they have viewed within MAGO Moon Museum as RWAs, enabling a deeper engagement with the artist’s worldview and creative philosophy.

    Overview

    About “$VIVI RWA MARKET”

    The “$VIVI RWA MARKET” is an RWA marketplace dedicated to the acquisition of artworks and is embedded within the online museum MAGO Moon Museum.

    Seamless Pathway from Viewing to Purchase

    Users can seamlessly transition from an artwork’s exhibition page to its corresponding RWA product page, creating a unified experience from online viewing to ownership.

    Integration of Physical and Digital Asset Design

    Each artwork includes the following structured information:

    • Physical artwork details (size, materials, condition, provenance)
    • High-resolution digital data generated through AI 3D scanning
    • Artist profile and project background information
    • along with other curated metadata.

    This structure allows users to acquire artworks with a proper understanding of their cultural and artistic value.

    Ecosystem Holding Functionality

    Acquired works will gradually gain viewing and management functionality within the VIVI ecosystem. While future integration with VIVI COiN is under consideration, the current initiative is focused solely on enhancing the preservation, appreciation, and understanding of the artworks.

    About LEGENDARY HUMANITY and the VIVI PROJECT

    LEGENDARY HUMANITY promotes the “VIVI PROJECT,” which digitizes legendary masterpieces created by humanity into digital assets using high-precision, non-contact, AI-integrated 3D scanning technology. The project operates under the vision of “Bringing the beauty of humanity to AI and the future.”

    Targeted assets include:

    • Legendary fashion collections
    • Historical architecture and cultural masterpieces
    • Famous trading cards
    • Artworks, including those exhibited at MAGO Moon Museum
    • and other assets that can be described as humanity’s masterpieces.

    The VIVI PROJECT aims to:

    • Digitize assets as digital cultural heritage
    • Tokenize them as RWAs for global circulation
    • Exhibit them in both online and physical museums
    • thereby building new infrastructure that harmonizes cultural and economic value.

    NEXT SOCIETY (Gacha Location): https://nextsociety.lhvivi.io

    RWA Market Roadmap

    The launch of the “$VIVI RWA MARKET” represents the first phase of RWA market functionality within the VIVI PROJECT. Planned future developments include:

    • VIVI FASHION (RWA for the fashion domain)
    • VIVI TRADING CARD (RWA for the trading card domain)
    • VIVI ART WORK (RWA for art collections)
    • with future integration under consideration.

    About MAGO Moon Museum

    MAGO Moon Museum is an online museum created by contemporary artist Shingo Nagasaka, whose works explore themes related to electronic waste issues in Agbogbloshie, Ghana.

    The museum provides an online space to view Nagasaka’s representative works, including pieces created from discarded electronic components found in Ghanaian slums, as well as series examining the concept of “Sustainable Capitalism.”

    With the implementation of the “$VIVI RWA MARKET,” viewers can deepen their understanding of the artworks while acquiring pieces aligned with the artist’s philosophy in an appropriate and structured manner.

    Future Developments

    Building on this initiative, LEGENDARY HUMANITY plans to:

    • Expand collaborations with masterpieces across different regions and genres
    • Strengthen international networks with artists, collectors, and researchers
    • Advance technological development for the preservation of cultural assets for future generations
    • and continue developing as a platform that passes humanity’s masterpieces into the future through real-world assets.

    Media Contact

    Company Name: LEGENDARY HUMANITY PTE. LTD.

    Address: 105 Cecil St, The Octagon 24F-2, Singapore 06953

    Representative: Takamasa Suzuki, LEGENDARY HUMANITY / VIVI PROJECT Public Relations Desk

    Email: info@lhvivi.com

    Related URL: $VIVI RWA MARKET https://mondo.lhvivi.io

  • Zeagoo Valentine’s Day Styling Guide: Unlock a New Definition of Romance with an Independent Stance

    As Valentine’s Day approaches, discussions about love once again take center stage. Nowadays, the ways to celebrate “love” are becoming more diverse and autonomous. It can be a sweet rendezvous between lovers, a warm gathering among friends, or even a pure act of self-reward. On this holiday dedicated to expressing emotions, dressing is not just about external appearance; it’s also a declaration of one’s inner attitude and self-charm.

    This year, Zeagoo is here to explore the various possibilities of this holiday with you. From romantic dates to get-togethers with girlfriends, and from external styling to inner attitudes, let’s interpret the confident declaration of “Be Different, Be You” through fashion.

    Go on a Heart-fluttering Date and Let Prints Tell Your Romantic Story

    Imagine a gentle breeze blowing in the evening, with the hem of your skirt swaying gracefully as you walk. On this special day, a dress that accentuates a woman’s gentle temperament is an excellent choice for creating a romantic atmosphere.

    The Zeagoo floral-printed chiffon dress features a lightweight and flowing fabric that outlines smooth lines. The delicate prints seem to bring a spring garden to life right on your body. Whether it’s the exquisite waist-cinching design or the fluttering skirt, it subtly amplifies female charm, making you the focal point of your date. Pair it with simple jewelry and a pair of elegant low-heeled shoes, and you can effortlessly create a heart-fluttering romantic look.

    Get Together with Girlfriends and Interpret a Confident Aura with Simplicity

    Valentine’s Day isn’t just about romantic love; it’s also about the precious friendships in life. A get-together with girlfriends is a time for laughter and sharing, and your outfit should be comfortable and easy-going while still reflecting your unique personality.

    A well-tailored cotton shirt paired with high-waisted wide-leg pants strikes the perfect balance between comfort and style. Zeagoo’s shirt, crafted from lightweight and breathable cotton fabric, features a sleek and tailored cut. It can be worn alone to showcase a polished demeanor or layered as an inner piece. When meeting friends, this look requires no effort yet exudes a natural, composed aura, reflecting the independent and confident essence of modern women.

    Loving Yourself Is the Most Touching Chapter of Valentine’s Day

    This Valentine’s Day, whether your plan is to spend time with your significant other, get together with friends, or enjoy a peaceful moment alone, always remember: the one most deserving of your love is always yourself. Put on clothes that make you feel confident and comfortable, and embrace your own special moments.

    Zeagoo has always believed that fashion is a way to express oneself. The brand encourages every woman to be brave and be herself, dressing in a way that stands out from the crowd. This is exactly what Zeagoo advocates with its motto “Be Different, Be You.”

    This Valentine’s Day, let your external styling and inner confidence bloom simultaneously. Zeagoo is here with you to create a unique kind of romance through fashion.

    For more information, please visit the Zeagoo website and Amazon storefront, or connect with Zeagoo on Facebook and Instagram.

    Zeagoo

    Charlotte Liu

    pr@zeagoo.com

    New York, US

    https://zeagoo.com

  • Super Bowl Meets Valentine’s Day: PINSPARK Ignites Couples’ Sweetness on the Sports Field with Athletic Wear

    As the Super Bowl approaches, sports enthusiasm and festive atmosphere intertwine and heat up across the United States. This year, in addition to the intense showdowns and spectacular halftime shows, the “outfit coordination” between couples has quietly become a focus outside the field. When football collides with Valentine’s Day, athletic style and a romantic ambiance spark brand-new inspiration. PINSPARK timely launches a spring-summer collection of athletic wear for couples that combines comfort and trendiness, providing young lovers with fashion solutions for everything from watching games to going on dates.

    From the Super Bowl to Valentine’s Day: Harmonious Companionship Off the Field

    The Super Bowl weekend is not just a carnival for football; it’s also a time for couples to showcase their outfit coordination. This has become a consensus among many young couples. Whether watching the game together at home or gathering with friends at a bar, comfortable yet stylish outfits are the ideal choice for sharing the moment.

    PINSPARK keenly captures this scenario demand. Taking “Love in Motion” as its inspiration, it cleverly blends sports functionality, trendy design, and couple-interaction elements to create a clothing collection suitable for joint game-watching, daily dating, and light outdoor activities. This allows couples to display their coordination and individuality through their outfits while remaining in a relaxed state.

    Game-Watching Outfit Guide for Couples: Comfortable and Stylish, Sweetening the Moment

    Male Outfits: Lightweight and Trendy, Moving with Dynamism

    Males can opt for PINSPARK’s classic lightweight athletic hoodies. The fabric is soft and breathable, ideal for long-term wear. Paired with the brand’s matching casual pants and versatile trendy sneakers, they maintain a sporty feel without sacrificing simplicity and fashion. For details, choose accessories in the same color scheme as the supported team, such as hats or socks, to instantly ignite game-watching enthusiasm.

    Female Outfits: Feminine and Energetic, Playfully Echoing

    Females can select PINSPARK’s coordinated athletic sets that echo their partner’s color scheme. A cropped top paired with high-waisted casual pants highlights an energetic silhouette. Layered with an oversized fashionable hoodie, it creates a laid-back game-watching vibe while also being adaptable to different temperatures.

    In addition to the main outfits, couples can use small props like cheering wristbands and matching phone cases to add fun and a sense of ritual. They can even try team-themed nail art or face painting together, turning the game-watching experience into an interactive couples’ date.

    Sports Can Be Romantic: Nurturing Coordination Through Shared Passions

    Watching a game together is also a form of dating. PINSPARK hopes to convey the lifestyle concept that “sports can be very romantic” through this collection. Couples watching the game together, sharing exciting moments, exchanging opinions, and cheering for outstanding performances—these simple interactions are precisely the process of cultivating coordination and emotions through shared passions. And comfortable and fashionable outfits not only make each other’s looks complement each other but also add a relaxed and easygoing atmosphere to intimate moments.

    As Valentine’s Day approaches, PINSPARK has specially launched a range of Valentine’s Day limited-edition colored athletic outfits. The collection features romantic pink, warm gray, and white as the main tones. While continuing the brand’s comfortable and fashionable style, it helps couples confidently display the vitality of love.

    Welcome to visit thePINSPARK official flagship store and brand website to explore more Valentine’s Day limited-edition styles and get exclusive outfit inspiration.

    PINSPARK

    Charlotte Liu

    pr@pinspark.com

    New York, US

    https://pinspark.com